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Updated: Feb 14, 2026

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
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In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

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FLNCの変異を明らかにする:病気のメカニズムを研究するためのモデルとして,iPSC由来の神経細胞

Nassam M Daya1,2, Anne Schänzer3,4, Andreas Hentschel5

  • 1Ruhr University Bochum, BG University Hospital Bergmannsheil, Department of Neurology, Bochum, Germany, Ruhr-University Bochum, Bochum, Germany. nassam.daya@rub.de.

Skeletal muscle
|February 12, 2026
PubMed
まとめ

研究者らは,フィラミノパシー,まれな神経筋疾患に対する患者特有の骨格筋オーガノイドモデルを開発した. このモデルは,疾患の特徴を明らかにし,フィラミンC (FLNC) に関連する筋肉の弱さや心筋病の治療標的を特定するのに役立ちます.

キーワード:
病気モデリングファイラミノパシー (filaminopathies) とは,フィラミノパシー (filaminopathies) とは,フィラミノパシー (filaminopathies) とは,フィラミノパシーのことです.オルガノイド・オルガノイドとはiPSC iPSCは,インターネット上で

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