LAG3,CD4+ T

Abidan Ainiwaer1,2, Dewei Li3, Wenge Liu1

  • 1Basic Medical College, Xinjiang Medical University, Urumqi, Xinjiang, China.

Parasites & vectors
|February 12, 2026
PubMed
まとめ

リンパ球活性化遺伝子-3 (LAG3) は,初期のエチノコックス・マルチロキュラリス感染中に抗寄生体CD4+T細胞応答を制限する. LAG3を標的とした治療は,アルベオラエキノココシス (AE) の治療戦略を提供できるかもしれないが,肝臓損傷を悪化させないために慎重にタイミングを決めなければならない.

関連する概念動画

Epiphytes, Parasites, and Carnivores02:40

Epiphytes, Parasites, and Carnivores

Plants often form mutualistic relationships with soil-dwelling fungi or bacteria to enhance their roots’ nutrient uptake ability. Root-colonizing fungi (e.g., mycorrhizae) increase a plant’s root surface area, which promotes nutrient absorption. While root-colonizing, nitrogen-fixing bacteria (e.g., rhizobia) convert atmospheric nitrogen (N2) into ammonia (NH3), making nitrogen available to plants for various biological functions. For example, nitrogen is essential for the...
16.9K
Humoral Immune Responses01:36

Humoral Immune Responses

Overview
84.2K
Diversity in Cell Signaling Responses01:22

Diversity in Cell Signaling Responses

The physiological function of a cell and cellular communication are outcomes of a range of extrinsic signals, intracellular signaling pathways, and cellular responses. No two cell types express the same repertoire of signaling components. Receptors are highly selective for their cognate ligands, but once activated, they can alter multiple cellular processes such as DNA transcription, protein synthesis, and metabolic activity. 
Graded and Abrupt Responses
Some signaling systems generate...
8.0K
Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

Overview
84.3K
Cells of the Adaptive Immune Response01:23

Cells of the Adaptive Immune Response

The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
9.1K
Cells of the Innate Immune Response01:28

Cells of the Innate Immune Response

The innate immune response is an immediate and non-specific response against pathogens, acting swiftly to prevent the spread of infections. The primary cells involved in this response are phagocytes and natural killer (NK) cells.
Phagocytes
Phagocytes police the peripheral tissues by removing cellular debris and responding to the invasion of foreign substances or pathogens. Many phagocytes attack and remove microorganisms even before lymphocytes detect them. The human body has two general...
9.5K