レミマゾラムは,フェロプトーシスを阻害することによって急性肺損傷を緩和します:実験的検証を伴うマルチオミックスのシステム薬理学アプローチ

Ruohan Li1, Lingzhi Qin1, Jiajia Ren1

  • 1Department of Critical Care Medicine, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 Xi 5 Lu, Xi'an, 710004, Shaanxi, PR China.

PubMed
まとめ

レミマゾラムは,細胞死経路であるフェロプトーシスを阻害することによって,急性肺損傷を緩和します. この研究は,その保護効果がヘム酸化酵素-1 (HO-1) とSLC7A11-GSH-GPX4軸と関連していることを明らかにし,治療の可能性を示唆しています.

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