Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Natural and Artificial Concepts01:24

Natural and Artificial Concepts

578
In psychology, concepts can be divided into two categories: natural and artificial. Natural concepts are formed through direct or indirect experiences. For example, consider the concept of snow. If you live in a place with regular snowfall, such as Essex Junction, Vermont, you know snow through direct experiences. You’ve seen it fall, touched it, shoveled it, and played in it. You recognize its texture, appearance, and even its smell. In contrast, if you live on an island like Saint...
578
Multipotency of Hematopoietic Stem Cells01:19

Multipotency of Hematopoietic Stem Cells

3.9K
The hematopoietic stem cells or HSCs are multipotent, meaning they can differentiate and give rise to all blood and immune cells. HSCs are maintained in the quiescent stage until an external stimulus initiates their differentiation. The multipotent HSCs exist as two heterogeneous populations, long-term repopulating cells (LTRC) and short-term repopulating cells (STRC). The two HSC populations have different surface markers or receptors and are classified based on quiescence and long-term...
3.9K
Regulation of Hematopoietic Stem Cells01:01

Regulation of Hematopoietic Stem Cells

4.1K
All blood and immune cells are produced from the multipotent hematopoietic stem cells (HSCs) by the process of hematopoiesis. However, they all have a limited life span. In addition, many are depleted in immune surveillance or combatting an injury or infection. This makes blood one of the most regenerative tissues. Hematopoiesis helps replenish these blood and immune cells, restoring the body's normal functioning. However, overproduction of blood and immune cells can make them cancerous or...
4.1K
Somatic to iPS Cell Reprogramming01:29

Somatic to iPS Cell Reprogramming

2.7K
Reprogramming alters the gene expression in somatic cells, transforming them into induced pluripotent stem (iPS) cells over several generations. Scientists can reprogram cells by introducing genes for four transcription factors—Oct4, Sox2, Klf4, and c-Myc (OSKM) by viral or non-viral methods. These factors are also known as Yamanaka factors after Shinya Yamanaka, who first generated iPS cells using mouse skin cells. Yamanaka was awarded the Nobel Prize in Physiology or Medicine in 2012...
2.7K
What is Natural Selection?01:32

What is Natural Selection?

129.8K
Natural selection is an evolutionary process in which individuals with survival-promoting traits reproduce at higher rates. These favorable traits become more common within a population or species. Naturally selected traits initially arise via random genetic mutations. In order for selection to occur, there must be variation within a population, the trait controlling the variation must be heritable, and there must be an evolutionary advantage for variation in the trait.
129.8K
Nature and Nurture01:10

Nature and Nurture

22.4K
Many human characteristics, like height, are shaped by both nature—in other words, by our genes—and by nurture, or our environment. For example, chronic stress during childhood inhibits the production of growth hormones and consequently reduces bone growth and height. Scientists estimate that 70-90% of variation in height is due to genetic differences among individuals, and 10-30% of variation in height is due to differences in the environments that individuals experience,...
22.4K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Photocatalytic Markovnikov-Selective Sulfonation of Alkynes for Indoline Synthesis.

The Journal of organic chemistry·2026
Same author

CD13 identifies S100A4<sup>+</sup> immunosuppressive monocytes and predicts temozolomide benefit in glioblastoma.

Biology direct·2026
Same author

Reconfigurable logic gates and latches in noise-driven bistable systems: A mean first-passage time approach.

Physical review. E·2026
Same author

Cooperative and competitive hyperorder interactions nonlinearly reshape the collective dynamics in complex networks.

Physical review. E·2026
Same author

Integrated network toxicology and experimental validation to investigate potential mechanisms associated with aspartame-induced malignant phenotypic changes in colorectal cancer.

Naunyn-Schmiedeberg's archives of pharmacology·2026
Same author

Toward precise management of groundwater by combined heavy metal(loid)s contamination at industrial sites: A machine learning driven source-to-risk zoning framework.

Environmental pollution (Barking, Essex : 1987)·2026

関連する実験動画

Updated: Feb 14, 2026

Artificial Antigen Presenting Cell aAPC Mediated Activation and Expansion of Natural Killer T Cells
13:18

Artificial Antigen Presenting Cell aAPC Mediated Activation and Expansion of Natural Killer T Cells

Published on: December 29, 2012

18.6K

自然と人工の血液形成細胞の再プログラム

Dong Yu1, Wenpei Liu1, Feng Liu1

  • 1Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine (Shanghai), Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Cellular reprogramming
|February 13, 2026
PubMed
まとめ
この要約は機械生成です。

血液形成細胞の再プログラミングは,血液または免疫細胞を別の血液または免疫細胞に変換し,病気の理解と治療の可能性を秘めています. 技術の進歩により,効率と臨床使用が向上していますが,依然として課題が残っています.

キーワード:
細胞の再プログラミング造血細胞は,血球形成細胞である.誘導体を再プログラムする誘導体腫瘍のマイクロ環境

さらに関連する動画

Isolation Method for Long-Term and Short-Term Hematopoietic Stem Cells
06:41

Isolation Method for Long-Term and Short-Term Hematopoietic Stem Cells

Published on: May 19, 2023

2.6K
Author Spotlight: Advancing Hematopoietic Research Using Stromal Cell Isolation for Single Cell Sequencing
05:27

Author Spotlight: Advancing Hematopoietic Research Using Stromal Cell Isolation for Single Cell Sequencing

Published on: January 26, 2024

1.6K

関連する実験動画

Last Updated: Feb 14, 2026

Artificial Antigen Presenting Cell aAPC Mediated Activation and Expansion of Natural Killer T Cells
13:18

Artificial Antigen Presenting Cell aAPC Mediated Activation and Expansion of Natural Killer T Cells

Published on: December 29, 2012

18.6K
Isolation Method for Long-Term and Short-Term Hematopoietic Stem Cells
06:41

Isolation Method for Long-Term and Short-Term Hematopoietic Stem Cells

Published on: May 19, 2023

2.6K
Author Spotlight: Advancing Hematopoietic Research Using Stromal Cell Isolation for Single Cell Sequencing
05:27

Author Spotlight: Advancing Hematopoietic Research Using Stromal Cell Isolation for Single Cell Sequencing

Published on: January 26, 2024

1.6K

科学分野:

  • 血液学 ヘマトロジ
  • 免疫学 免疫学とは
  • 細胞生物学 細胞生物学
  • 再生医学は,再生医療である.

背景:

  • 血液形成細胞の再プログラミングは,血液または免疫細胞の1つのタイプを別のタイプに変換することを意味します.
  • このプロセスは,血液形成,疾患メカニズムを理解し,新しい治療法を開発するために不可欠です.
  • それは,さまざまなヒントやストレス要因の影響を受けた,トランスディフェレンチエーション,ディディフェレンチエーション,または可塑性によって発生します.

研究 の 目的:

  • 血液形成細胞再プログラムが,血液学と免疫学を進歩させる可能性を見直す.
  • 細胞変換におけるメカニズム,課題,新興戦略について議論する.
  • パーソナライズされた細胞治療の将来の展望を強調する.

主な方法:

  • 造血細胞再プログラムに関する現在の文献のレビュー.
  • マルチオミクス,遺伝子編集,化学生物学における進歩の分析.
  • プロトコル開発のための人工知能と単細胞分析の統合.

主要な成果:

  • 造血細胞の再プログラミングは,血液細胞の発達と免疫疾患を理解するための変革の可能性を秘めています.
  • 技術の進歩により,再プログラミングの有効性と臨床的翻訳性が向上しています.
  • 課題には,低効率,フェノタイプの不安定性,および安全性に関する懸念が含まれます.

結論:

  • 造血細胞の再プログラミングは,腫瘍学,免疫学,再生医療におけるパーソナライズド・セル・セラピーの有望な経路を提供します.
  • 提供,特異性,および長期的な有効性における課題を克服することは,臨床実現の鍵です.
  • 最先端技術の統合は,将来の進歩にとって不可欠です.