猫の注射でSysmex XT-2000iVとSysmex XN-1000Vで評価されたデルタ総核細胞の比較
Manuela Zanetti1, Sara Meazzi2,3, Saverio Paltrinieri2
1Antech Diagnostics, Mars Petcare Science & Diagnostics, 20129 Milan, Italy.
Animals : an open access journal from MDPI
|February 13, 2026
まとめ
Sysmex XT-2000iVとXN-1000Vの分析器から得られた核細胞数 (ΔTNC) の比率は,噴出性FIPを含む猫の出血を診断する際に,同様の精度を示した. いくつかのバイアスにもかかわらず,XT-2000iVからのカットオフは,両方のプラットフォームのサンプルを効果的に分類しました.
科学分野:
- 獣医の血液学 獣医の血液学
- 診断用サイトロジー
- 比較病理学の比較病理学について
背景:
- Sysmex XT-2000iVからの核細胞数比 (ΔTNC) は,猫の出血分析のための検証されたツールです.
- ΔTNC>2.5は,エフシューシブ猫性感染症炎 (FIP) の診断において高い精度を示しています.
研究 の 目的:
- Sysmex XT-2000iVとSysmex XN-1000Vのアナライザー間の ΔTNC測定の診断ユーティリティを比較する.
- これらの分析器の性能を様々な種類の猫の排泄物で評価する.
主な方法:
- 45匹の猫の排泄液サンプルを,Sysmex XT-2000iV (WBC-BASO,WBC-DIFF,DTNC-XTを測定する) とSysmex XN-1000V (TNC-WNR,TNC-WDF,DTNC-XNを測定する) の両方を用いて分析した.
- 統計分析には,PassingとBablokの回帰とBland-Altmanのプロットが含まれて,2つの分析器の ΔTNC 値との一致とバイアスを評価しました.
主要な成果:
- 2つの分析器の間で,評価されたすべてのパラメータにおいて,有意な差異は観察されなかった.
- パスとバブロク回帰では,ΔTNC-XTとΔTNC-XNの傾きが1.612で,切断点が-0.744であることが明らかになった.
- 陽性バイアス (4.382) は,特に高い ΔTNC 値で観察され,分析器の間の比率と定数バイアスを示した.
結論:
- 特定されたバイアスにもかかわらず,XT-2000iVカットオフを使用する際に,猫の出血は両方の分析器によって同様に分類されました.
- Sysmex XN-1000Vは,ネコの排泄物の ΔTNC 分析のために XT-2000iV と交換して使用できます.
- 両方の分析器は,FIPを示唆するサンプルを特定する上で高い精度を保ちます.
キーワード:
デルタ - FIPIPシスメックスXN-1000V猫や猫たちのこと.洞穴内流出 (cavitary effusions) とは,洞穴内流出 (cavitary effusions) とは,洞穴内流出 (cavitary effusions) とは,洞穴内流出 (cavitary effusions) とは,洞穴内流出 (cavitary effusions) とは,洞穴内流出 (cavitary effusions) とは,洞穴内流出 (cavitary effusions) とは,洞穴内流出 (cavitary effusions) とは,洞穴内流出 (cavitary effusions) とは,洞穴内流出 (cavitary effusions) とは,洞穴内流出 (cavitary effusions) とは,洞穴内流出 (cavitary effusions) とは,
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