血清中の25-ヒドロキシビタミンD濃度と関連して,骨格筋の微血管性の定量超音波評価

Nusret Seher¹, Lütfiye Parlak², Halil Özer¹

¹Department of Radiology, Medical Faculty, Selcuk University, 42130 Konya, Turkey.

Diagnostics (Basel, Switzerland)

|February 13, 2026

まとめ

血清の25-ヒドロキシビタミンDレベルは,筋肉のサイズに関係なく,骨格筋の微小血管性と強く関連しています. この研究は,ビタミンDを強調しています.

科学分野:

筋肉骨の健康と画像科学. 筋肉骨の健康と画像科学.

背景:

ビタミンDは,筋骨格系の健康に不可欠です.
骨格筋のマイクロ血管注射における正確な役割は不明である.
この関連性を定義するには,定量画像が必要である.

研究の目的:

血清の25-ヒドロキシビタミンD [25(OH) D]濃度と骨格筋の微血管性との関係を調査する.
定量的な評価のために,超音波ベースの高度なマイクロ血管画像法を使用します.

主な方法:

141人の健康な成人を対象とした横断的な研究で,血清25 ((OH) Dレベル (<20 ng/mL vs. ≥20 ng/mL) によって層分化されました.
血管指数 (VI) を定量化するために使用される超微血管図.
筋肉の横断面 (CSA) は, flexor carpi radialis, biceps brachii,および tibialis anteriorで測定されました.

主要な成果:

グループ間の筋肉CSAの有意な差異はありません.
すべての筋肉で血清25[OH]D濃度が高くなった参加者のVIが著しく高かった (p<0.001).
バイセプス・ブラカイVIは,グループを区別する際の優れた診断性能 (AUC = 0.992) を示した.

結論:

血清25(OH) Dレベルは,筋肉のサイズに関係なく,骨格筋の微血管性と強く関連しています.
ウルトラ・マイクロ・アニオグラフィは,ビタミンDの状態に関連するマイクロ血管の変化を評価するための有望な非侵襲的ツールです.

キーワード:

骨格筋は,骨格の筋肉で,骨格筋は骨格筋で,骨格筋は骨格筋で,骨格筋は骨格筋で,骨格筋は骨格筋で,骨格筋は骨格筋で,骨格筋は骨格筋で,骨格筋は骨格筋で.ウルトラ・マイクロ・アニオグラフィー超音波による超音波検査ビタミンD ビタミンD

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