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Updated: Feb 14, 2026

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トリプルネガティブな乳がんにおけるERK5シグナリングの文脈特異的な効果を解析する

Katherine L Hebert1, Sarah B Knopf1, Thomas Cheng1

  • 1Department of Medicine, Section of Hematology & Medical Oncology, Tulane University School of Medicine, New Orleans, LA 70112, USA.

Cancers
|February 13, 2026
PubMed
まとめ

細胞外信号調節キナーゼ5 (ERK5) は,腫瘍の微環境と細胞の運動性を調節することによって,三重陰性乳がん (TNBC) の進行に影響を与えます. ERK5をターゲットにすることは,攻撃的なTNBCに対する新しい治療戦略を提供することができる.

キーワード:
ERK5 ERK5 ERK5 ERK5MAPKK (マプク) とはエピテリアからメゼンキマへの移行細胞外マトリックスマクロ生理学的なモデル

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