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Updated: Feb 14, 2026

Murine Surgical Model of Topical Elastase Induced Descending Thoracic Aortic Aneurysm
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Murine Surgical Model of Topical Elastase Induced Descending Thoracic Aortic Aneurysm

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内皮壁障害から循環するバイオマーカーへ:胸腔大動脈動脈瘤と解剖におけるクラウジン-5の臨床的可能性

Qianhui Ding1, Xueyuan Yang1, Zitian Duan1

  • 1Department of Physiology and Pathophysiology, State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University School of Basic Medical Sciences, Beijing 100191, China.

Journal of clinical medicine
|February 13, 2026
PubMed
まとめ

クラウジン-5 (CLDN5) は,胸部大動脈動脈瘤および解剖 (TAAD) の患者で上昇しています. このタンパク質は診断の可能性を示しており,その機能不全は内皮の障壁機能を損なっており,新しいTAAD診断戦略を提供している.

キーワード:
バイオマーカーのバイオマーカークラウディン5 クラウディン5内皮細胞の内皮細胞細胞の内皮細胞である.胸前大動脈動脈瘤と解剖の解剖緊密な交差点の緊密な交差点について

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