産後成長障害の予測因子とリスクスコアリング 産後成長障害の予測因子とリスクスコアリング 産後体重が非常に低い乳児における産後成長障害の予測因子とリスクスコアリング
Nutcha Singhasem1, Gunlawadee Maneenil1, Anucha Thatrimontrichai1
1Division of Neonatology, Department of Pediatrics, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand.
Nutrients
|February 13, 2026
まとめ
産後成長不全 (PGF) は,非常に低出生体重 (VLBW) の多くの乳児に影響します. 主なリスク要因には,低出生体重,複数出産,妊娠合併症などがあり,早期発見と介入に役立ちます.
科学分野:
- ネオナタロジー (新生児科学)
- 小児の成長と発達について
- 産周医学は,産周医学である.
背景:
- 産後成長不全 (PGF) は,非常に低出生体重 (VLBW) の乳児における重大な懸念事項です.
- PGFのリスクのある新生児の早期発見は,適切な介入に不可欠です.
研究 の 目的:
- VLBWの乳児におけるPGFに関連した要因を特定する.
- PGFに敏感な新生児の早期リスク層分化の予測モデルを開発する.
主な方法:
- VLBWの乳児 (2014-2024) の遡及的なコホート研究.
- PGFは,2013年のフェントン成長グラフを使用して定義されています.
- 多変数ロジスティック回帰と受信機操作特性 (ROC) 曲線解析を使用した.
主要な成果:
- 481人のVLBWの乳児のうち,69.4%がPGFを経験しました.
- 重要な予測要因には,出生体重<750gおよび750-1000g,複数出産,妊娠による高血圧,オリゴヒドラムニオス,産前コルチコステロイドの欠如,配方/混合栄養が含まれていました.
- 開発されたリスクスコアは,良好な予測性能 (AUC 0.736) を示した.
結論:
- 低出生体重 (<1000g),複数出産,妊娠による高血圧,オリゴヒドラムニオス,産前コルチコステロイドの欠如,および特定の給餌方法は,PGFの主要な予測要因です.
- 派生したリスクスコアは,リスクの高いVLBWの乳児を早期に特定し,標的の栄養支援に役立ちます.
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