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Updated: Feb 14, 2026

Standardization and Maintenance of 3D Canine Hepatic and Intestinal Organoid Cultures for Use in Biomedical Research
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UPLC-MS/MSに基づいたプニカラギンの肝腸ファーストパス効果と分泌経路の体系的な研究

Zixin Chen1, Zhanying Chang1, Pengxia Yao1

  • 1College of Pharmacy, Xinjiang Medical University, Urumqi 830017, China.

Molecules (Basel, Switzerland)
|February 13, 2026
PubMed
まとめ

石榴のプニカラギンは,肝臓の処理ではなく,広範な腸内代謝による口腔での生物利用性が低い. この研究は,その腸内処理と除去を明確にし,将来の配送戦略を支援します.

キーワード:
UPLC-MS/MS/MSで表示される生物学的利用可能性排泄は,排泄によって起こります.ファーストパス効果です.腸内代謝による代謝である.ファルマコキネティクス 薬理学プニカラギン (プニカラギン) とは

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