関連する実験動画

Updated: Feb 14, 2026

In vitro Uncoating of HIV-1 Cores
10:49

In vitro Uncoating of HIV-1 Cores

Published on: November 8, 2011

16.3K

低分子量硫酸キトーサン微粒子はHIV-1を効果的に結合する In Vitro:微生物殺菌剤の応用の可能性

Sergio A Bucarey1, Verónica Ramos2, Alejandro A Hidalgo3

  • 1Centro Biotecnológico Veterinario, Biovetec, Departamento de Ciencias Biológicas, Facultad de Ciencias Veterinarias y Pecuarias, Universidad de Chile, Santa Rosa 11735, La Pintana, Santiago 8820000, Chile.

Molecules (Basel, Switzerland)
|February 13, 2026
PubMed
まとめ

新しい硫酸キトーサン微粒子は,HIV-1に対する強力な抗ウイルス活性を示しています. これらの新しい微粒子は,ウイルスの負荷を効果的に軽減し,潜在的な局所的微生物殺菌剤の応用のために従来のヘパリノイド材料を上回ります.

キーワード:
HIV-1 エントリーインhibition HIV-1 エントリーインヒビレーションバイオミテック微生物殺菌剤ヘパラン硫酸ナトリウム模倣剤硫化キトーサン微粒子の硫化キトーサンウイルス・バインディング・デコイ戦略

さらに関連する動画

Preparation and Characterization of SDF-1α-Chitosan-Dextran Sulfate Nanoparticles12:00

Preparation and Characterization of SDF-1α-Chitosan-Dextran Sulfate Nanoparticles

Published on: January 22, 2015

13.0K
Visualization of HIV-1 Gag Binding to Giant Unilamellar Vesicle GUV Membranes08:21

Visualization of HIV-1 Gag Binding to Giant Unilamellar Vesicle GUV Membranes

Published on: July 28, 2016

9.4K

関連する概念動画

Polymers: Defining Molecular Weight01:01

Polymers: Defining Molecular Weight

Unlike small molecules with definite molecular weights, polymers are a mixture of individual polymer chains of varying lengths, each with a unique molecular weight.  So, the molecular weight of a polymer is expressed as an average value based on the average size of the polymer chains. The two most common forms of averages used for polymers are the number average molecular weight and weight average molecular weight.
The number average molecular weight (Mn) is the summation of the number...
3.9K
Polymers: Molecular Weight Distribution01:10

Polymers: Molecular Weight Distribution

For any given polymer, the weight average molecular weight (Mw) is higher than, if not equal to, the number average molecular weight (Mn). The only situation in which the weight average molecular weight and the number average molecular weight are equal is when a polymer consists only of chains with equal molecular weight. However, this never happens in a synthetic polymer, since it is difficult to control the polymerization process up to a molecular level with accuracy to a hundred percent.
4.9K
Molecular Weight of Step-Growth Polymers01:08

Molecular Weight of Step-Growth Polymers

Step growth polymerization involves bi or multifunctional monomers. Bifunctional monomers react to form linear step growth polymers, whereas multifunctional monomers react to form non-linear or branched polymers.
As the step-growth polymerization involves step-wise condensation of monomers, the molecular weight also builds up eventually. Consequently, high molecular weight polymers are obtained at the late stages of the polymerization, where 99% of monomers have been consumed.
The extent of the...
2.9K
Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

Anticoagulant Drugs: Low-Molecular-Weight Heparins

Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
2.0K
Applications of Molecular Taxonomy01:20

Applications of Molecular Taxonomy

Molecular taxonomy has revolutionized the understanding and classification of bacteria, providing precise insights into their diversity, evolutionary relationships, and ecological roles. By utilizing molecular techniques such as DNA sequencing and fingerprinting, researchers have made significant strides in various fields related to bacterial studies.Resolving Taxonomic AmbiguitiesMolecular taxonomy has been instrumental in distinguishing closely related bacterial species initially thought to...
583
Sulfate Attack on Concrete01:29

Sulfate Attack on Concrete

Sulfate attack on concrete is a deterioration process characterized by a whitish discoloration beginning at the edges and corners, accompanied by cracking and spalling. This phenomenon occurs when sulfates react with the components of hardened concrete, forming compounds like calcium sulfate and calcium sulfoaluminate which occupy more space than the substances they replace, causing the concrete to expand and disrupt.
Sulfates from sources like soil, groundwater, or industrial effluents...
787