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Updated: Feb 14, 2026

An Emerging Target Paradigm to Evoke Fast Visuomotor Responses on Human Upper Limb Muscles
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挑戦的な標的をターゲットにするための新しいパラダイム:先進技術と分子接着剤の劣化剤の将来の方向性

Yifan Zhang1,2, Linlin Li1,2, Jiajia Xu1,2

  • 1State Key Laboratory of Natural Medicines, Jiang Su Key Laboratory of Drug Design & Optimization, China Pharmaceutical University, Nanjing 210009, China.

Molecules (Basel, Switzerland)
|February 13, 2026
PubMed
まとめ

分子粘着分解剤 (MGD) は,標的型タンパク質分解 (TPD) の新しい治療アプローチを提供します. これらの薬剤は,タンパク質クリアランスのためのE3リガース相互作用を安定させ,薬剤発見の有望性を示しています.

キーワード:
ドラッグ・ディスカバリー・メソッド分子接着剤分解剤 分子接着剤分解剤標的となるタンパク質の分解を狙った.

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