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Updated: Feb 14, 2026

Author Spotlight: High-Throughput Screening to Obtain Crystal Hits for Protein Crystallography
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Author Spotlight: High-Throughput Screening to Obtain Crystal Hits for Protein Crystallography

Published on: March 10, 2023

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タンパク質結晶のダイレクトフェッシング ハイブリッド差分マップアルゴリズム

Hongxing He1, Yang Liu1, Wu-Pei Su2

  • 1Department of Physics, School of Physical Science and Technology, Ningbo University, Ningbo 315211, China.

Molecules (Basel, Switzerland)
|February 13, 2026
PubMed
まとめ

新しいハイブリッド差分マップ (HDM) アルゴリズムは,X線 difraktionデータから直接タンパク質構造の決定を改善します. HDMは,伝統的な方法と比較して,相回収の成功率を大幅に高め,より堅牢な構造生物学分析を可能にします.

キーワード:
直接的な方法 直接的な方法ハイブリッド差の地図 ハイブリッド差の地図繰り返し投影アルゴリズムフェーズリトリーバルの検索タンパク質結晶学 タンパク質結晶学

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