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Updated: Feb 14, 2026

Author Spotlight: Developing a Rat Model for Weight-Bearing Intervention to Investigate Osteonecrosis of the Femoral Head
05:55

Author Spotlight: Developing a Rat Model for Weight-Bearing Intervention to Investigate Osteonecrosis of the Femoral Head

Published on: September 27, 2024

991

サーファクチン誘発のマクロファージ調節の分子基礎と,薬剤による骨縮症におけるその影響 の病原性

Yuki Kodama-Maruyama1, Hiroki Tsurushima2, Ayaka Koga1,3

  • 1Division of Infections and Molecular Biology, Department of Advanced Pathophysiological Science, Kyushu Dental University, Kitakyushu 803-8580, Fukuoka, Japan.

International journal of molecular sciences
|February 13, 2026
PubMed
まとめ

自然化合物であるサーファクチン (Surfactin) は,薬剤による骨硬化症 (MRONJ) の治療において有望であることが示されています. 重要な免疫経路を調節することにより,炎症と骨の死滅を効果的に軽減し,この困難な状態に対する潜在的な新しい治療戦略を提供します.

キーワード:
AP-1からAP-1までIL-6は,IL-6と一致している.JAK/STAT についてMAPKK (マプク) とはマロンジ (Mronj) とは表面ファクトイン (surfactin) とは

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