関連する実験動画

Updated: Feb 14, 2026

Use of Shigella flexneri to Study Autophagy-Cytoskeleton Interactions
12:52

Use of Shigella flexneri to Study Autophagy-Cytoskeleton Interactions

Published on: September 9, 2014

16.4K

感染におけるチャペロン媒介によるオートファギーの重要な役割と分子メカニズム

Min Wang1,2,3, Min Wu1,2,3

  • 1Hengyang Medical School, University of South China, Hengyang 421001, China.

International journal of molecular sciences
|February 13, 2026
PubMed
まとめ

Chaperone-mediated autophagy (CMA) は,損傷したタンパク質を分解することによって,感染中に宿主防御に不可欠です. CMAをターゲットにすることは治療的可能性を秘めていますが,細胞特異的な役割は,最適な抗感染戦略をさらに調査する必要があります.

キーワード:
護衛が介したオートファギーは感染による感染です.リンソソーム関連膜タンパク質病原体は病原体である.

さらに関連する動画

Activating Autophagy by Aerobic Exercise in Mice08:44

Activating Autophagy by Aerobic Exercise in Mice

Published on: February 3, 2017

12.8K
Adenofection: A Method for Studying the Role of Molecular Chaperones in Cellular Morphodynamics by Depletion-Rescue Experiments12:34

Adenofection: A Method for Studying the Role of Molecular Chaperones in Cellular Morphodynamics by Depletion-Rescue Experiments

Published on: September 16, 2016

8.1K

関連する概念動画

Molecular Chaperones and Protein Folding03:00

Molecular Chaperones and Protein Folding

The native conformation of a protein is formed by interactions between the side chains of its constituent amino acids. When the amino acids cannot form these interactions, the protein cannot fold by itself and needs chaperones. Notably, chaperones do not relay any additional information required for the folding of polypeptides; the native conformation of a protein is determined solely by its amino acid sequence. Chaperones catalyze protein folding without being a part of the folded protein.
The...
19.9K
Molecular Chaperones and Protein Folding03:00

Molecular Chaperones and Protein Folding

15.1K
Defense Mechanism Against Infection01:26

Defense Mechanism Against Infection

Natural flora, body system defenses, and inflammation are natural barriers of the body against infectious agents regardless of previous exposure. Normal floras of the human body refer to the microbial population that colonizes the skin and mucous membranes.
In addition, many body organ systems have unique defenses against infection. The skin is an intact, multilayered surface preventing invasion by microorganisms unless impaired. Mucous membranes lining the mouth, nose, and eyelids are barriers...
9.8K
Autophagy01:27

Autophagy

Autophagy is a self-digesting process by which a cell protects itself from threats both within and outside the cell, ranging from abnormal proteins to invading bacteria. In this process, obsolete components of the cell and invading microbes are degraded by hydrolytic enzymes active in an acidic environment of the lysosomal lumen.
An autophagic pathway consists of a series of signaling events activated in response to diverse stress and physiological conditions such as food deprivation,...
5.9K
Critical Region, Critical Values and Significance Level01:16

Critical Region, Critical Values and Significance Level

The critical region, critical value, and significance level are interdependent concepts crucial in hypothesis testing.
In hypothesis testing, a sample statistic is converted to a test statistic using z, t, or chi-square distribution. A critical region is an area under the curve in  probability distributions demarcated by the critical value. When the test statistic falls in this region, it suggests that the null hypothesis must be rejected. As this region contains all those values of the...
13.4K
Critical Values01:31

Critical Values

A critical value is a definite value obtained from a particular probability distribution at a predecided confidence level (or a predecided significance level) for a given population parameter. The critical value provides demarcation that separates the sample statistics that are likely to occur from the ones that are unlikely to occur based on the given probability distribution and the population parameter to be estimated. The critical value for normal distribution is obtained from the z...
10.4K