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Updated: Feb 14, 2026

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
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遺伝神経疾患におけるDNMT1変異の機能的および表遺伝子学的結果

Jun-Hui Yuan1, Yujiro Higuchi1, Masahiro Ando1

  • 1Department of Neurology and Geriatrics, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8520, Japan.

International journal of molecular sciences
|February 13, 2026
PubMed
まとめ

DNAメチルトランスフェラーゼ1 (DNMT1) 変種は,神経変性症候群に影響を及ぼします. この研究は,新しいナノ孔配列決定法を使用して,患者における領域特有の機能的効果と表遺伝子学的変化を明らかにしています.

キーワード:
5mCCは5mCでした.DNMT1はDNMT1に該当する.メチル化のメチル化感覚神経病気が発症する.spinocerebellar ataxia spinocerebellar ataxia spinocerebellar ataxia spinocerebellar ataxia spinocerebellar ataxia spinocerebellar ataxia spinocerebellar ataxia spinocerebellar ataxia spinocerebellar ataxia spinocerebellar ataxia spinocerebellar ataxia spinocerebellar ataxia spinocerebellar ataxia spinocerebellar ataxia spinocerebellar ataxia spinocerebellar

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