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Updated: Feb 14, 2026

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慢性的なストレスは,HPA軸不調およびGR核転移障害による時間依存的な骨の喪失につながります

Yupeng Yan1, Jiaxin Li1, Zhengmin Lu1

  • 1Institute of Basic Theory for Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China.

International journal of molecular sciences
|February 13, 2026
PubMed
まとめ

慢性的なストレスは,下垂体-下垂体-腎上腺 (HPA) 軸を混乱させ,グルココルチコイド受容体 (GR) のシグナル伝達を損なうことで,骨粗鬆症を引き起こす. GRシグナリングの回復は,治療的なアプローチを提供することができます.

キーワード:
HPA軸は,HPA軸と一致する.骨の損失は,骨の喪失によって引き起こされる.慢性的なストレスはストレスです.うつ病 うつ病 うつ病 うつ病 うつ病 うつ病 うつ病グルココルチコイド受容体は,グルココルチコイドに対する耐性

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