関連する実験動画

Updated: Feb 14, 2026

Engineering Oncogenic Heterozygous Gain-of-Function Mutations in Human Hematopoietic Stem and Progenitor Cells
12:04

Engineering Oncogenic Heterozygous Gain-of-Function Mutations in Human Hematopoietic Stem and Progenitor Cells

Published on: March 10, 2023

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STAT3R152W 変異モデルは,血液形成集団の時間的変化を明らかにした

Jakub Jankowski1, Jichun Chen2, Sung-Gwon Lee1

  • 1Section of Genetics and Physiology, Laboratory of Cell and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, MD 20892, USA.

International journal of molecular sciences
|February 13, 2026
PubMed
まとめ

STAT3 R152Wの変種は,免疫機能の調節不全を引き起こすが,自己免疫性の発達のコファクターとして作用する. このマウスモデルは,先天性および適応性免疫の複雑な変化を時間とともに明らかにしています.

キーワード:
STAT3では,STAT3が表示される.ゲルムライン突然変異免疫学 免疫学とはミッセンセスの変異はミッセンセスの変異です.

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