PRKACB,

Weidan Xiao1, Zhengmao Liu2, Qijuan Zhang2

  • 1Metabolic Bone Disease Clinic, The Affiliated Hospital of Wuhan Sports University, Wuhan, Hubei Province, China.

PubMed
まとめ

タンパク質キナーゼcAMP依存型触媒β (PRKACB) は,コンドロサイトを炎症性損傷から保護する. PKA/CREB経路経由でPRKACBを活性化すると,細胞の生存能力が向上し,炎症が軽減され,PRKACBが潜在的骨格関節炎治療標的であることを示唆しています.

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