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Updated: Feb 14, 2026

Production and Titering of Recombinant Adeno-associated Viral Vectors
08:35

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CHO細胞におけるブラスティシジン選択と組み合わせた,MAR強化トランポゾンベクトルによって媒介される再結合mAbsの効率的な生成

Xiaoyin Wang1,2, Xuelian Han1, Ting Liu1

  • 1School of Basic Medical Sciences, Henan Medical University, Xinxiang 453003, China.

Acta biochimica et biophysica Sinica
|February 13, 2026
PubMed
まとめ

新しいMARベースのpiggyBacトランポゾンシステムは,CHO細胞における再結合抗体の生成を大幅に強化します. この方法は,クローン選択の効率を向上させ,治療用抗体製造のためのより高い収量と長期的な発現安定につながります.

キーワード:
CHO細胞とは抗体は抗体として存在します.ブラスティシジン (Blasticidin) とはマトリックスアタッチメント領域 (マトリックスアタッチメント領域)piggyBac トランスポーソン

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