レッドイーストライス関連腎臓機能障害の1年間の追跡調査: 2件の症例報告
Moe Ozawa1, Yuki Kawai1, Jin Oshikawa2
1Department of Nephrology and Hypertension, Saiseikai Yokohamashi Nanbu Hospital, Yokohama, JPN.
Cureus
|February 13, 2026
まとめ
レッドイーストライスサプリメントは腎臓の損傷とファンコニ症候群を引き起こしました. 治療中止は2人の患者で腎臓の部分的または完全な回復をもたらし,時間の経過とともに徐々に改善することを示唆しました.
科学分野:
- ネフロロジーはネフロロジーを用います.
- 薬理学 薬理学とは
背景:
- レッドイーストライス (RYR) サプリメントは,高脂血症に使用されます.
- RYRサプリメント (Beni-kojiタブレット) は,腎機能不全のために日本でリコールされました.
- RYR誘発性腎機能不全は,ファンコーニ症候群と推定グローメルーラ濾過率の低下を引き起こす可能性があります.
研究 の 目的:
- ベニ・コジ錠剤の投与を中止した後の長期的な腎臓のアウトカムを調べる.
- RYR誘発性腎中毒症患者の腎機能の回復について報告する.
主な方法:
- ベニ・コジの錠剤を服用した後の腎機能不全を患った2人の女性の症例報告.
- 治療中止後1年間,腎機能のフォローアップ.
- 1人の患者は,中止に加えて,コルチコステロイド療法を受けた.
主要な成果:
- ケース1:錠剤の服用中止後に腎臓の部分回復と安定化.
- ケース2:錠剤の中止とコルチコステロイド治療後の腎臓の完全な回復と安定化.
- 両症例とも6ヶ月後に腎臓の回復が安定したことを示した.
結論:
- 腎機能は,Beni-koji錠剤を中止した後,徐々に回復する可能性があります.
- 廃止は,主要な経営戦略である.
- 持続的な腎臓の改善を確認するために,少なくとも6ヶ月のフォローアップが推奨されます.
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