関連する実験動画
Updated: Jul 19, 2026

09:41
Reconstitution Of β-catenin Degradation In Xenopus Egg Extract
Published on: June 17, 2014
まとめ
この研究は,以前の記事のDOIを修正しています. 訂正されたDOIは,正確な科学的参照のために適切な引用と研究成果へのアクセスを保証します.
科学分野:
- ビビロメトリクス (Bibliometrics) とは
- 科学的出版物 科学的出版物
背景:
- 正確な引用は,科学的完全性にとって極めて重要です.
- デジタルオブジェクト識別子 (DOI) は,研究出版物をリンクするために不可欠です.
研究 の 目的:
- 以前に掲載された記事のデジタルオブジェクト識別子 (DOI) を修正します.
- 科学的研究の正確な参照とアクセシビリティを確保する.
主な方法:
- オリジナル出版物における誤ったDOIの識別.
- 正確なDOIを記載した訂正通知を発行します.
主要な成果:
- 記事のDOIは10.1159/000547402に訂正されました.
- 訂正は,研究の適切な引用と検索を容易にする.
結論:
- DOIを訂正することは,学術記録を維持するために不可欠です.
- DOIの正確性を保証することは,科学的研究の再現性と影響をサポートします.
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Proofreading
Synthesis of new DNA molecules starts when DNA polymerase links nucleotides together in a sequence that is complementary to the template DNA strand. DNA polymerase has a higher affinity for the correct base to ensure fidelity in DNA replication. The DNA polymerase furthermore proofreads during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.Errors during Replication Are Corrected by the DNA Polymerase EnzymeGenomic DNA is synthesized in...
Mismatch Repair
Overview
Proofreading
Synthesis of new DNA molecules starts when DNA polymerase links nucleotides together in a sequence that is complementary to the template DNA strand. DNA polymerase has a higher affinity for the correct base to ensure fidelity in DNA replication. The DNA polymerase furthermore proofreads during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.Errors during Replication Are Corrected by the DNA Polymerase EnzymeGenomic DNA is synthesized in...
Proofreading
Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore, it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
Errors During Replication are Corrected by the DNA Polymerase Enzyme
Errors During Replication are Corrected by the DNA Polymerase Enzyme
Mismatch Repair
Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
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