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レプチン受容体rs1137101の多形態化とレプチン-sOb-R軸の変異は,グジャラト州の人口の2型糖尿病リスクに寄与しています

Nishant Parmar1, Nirali Rathwa1, Roma Patel1

  • 1Department of Biochemistry, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat, India.

Frontiers in endocrinology
|February 13, 2026
PubMed
まとめ

LEPR rs1137101 A/Gポリモルフィズムは,グジャラト州の人口における2型糖尿病 (T2D) のリスクの増加と関連しています. この遺伝的変異は,レプチンと溶性レプチン受容体のレベルが変化するとともに,T2Dの感受性に寄与する可能性があります.

キーワード:
ディスリピデミア (Dyslipidemia) とはゲノタイプ-フェノタイプ相関関係ハプロタイプはハプロタイプです.レプチン レプチンシングルヌクレオチドポリモルフィズムである.2型糖尿病 2型糖尿病

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