デュアルキー遺伝子回路は,潰瘍性大腸炎の治療のために,安定的かつ自己調節性エンジニアリングされた細菌を可能にします

Shuaijie Ding1, Biao Yang1, Xinyu Li1

  • 1Institute of Health and Medicine (IHM), Hefei Comprehensive National Science Center, Hefei, Anhui, China.

まとめ

合成のダブルキー回路を搭載したエンジニアリングされたバクテリアは,安定した,抗生物質のないプラズミド維持を達成します. この生細菌療法では,タンパク質の放出を制御し,免疫応答を調節することによって,ネズミの腸炎を効果的に治療します.

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