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Improving Translational Accuracy02:07

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Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
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Improving Translational Accuracy02:07

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Uncertainty in Measurement: Accuracy and Precision03:37

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Scientists typically make repeated measurements of a quantity to ensure the quality of their findings and to evaluate both the precision and the accuracy of their results. Measurements are said to be precise if they yield very similar results when repeated in the same manner. A measurement is considered accurate if it yields a result that is very close to the true or the accepted value. Precise values agree with each other; accurate values agree with a true value. 
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Scientists typically make repeated measurements of a quantity to ensure the quality of their findings and to evaluate both the precision and the accuracy of their results. Measurements are said to be precise if they yield very similar results when repeated in the same manner. A measurement is considered accurate if it yields a result that is very close to the true or the accepted value. Precise values agree with each other; accurate values agree with a true value.  Highly accurate...
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The Sense of Self: Reflected Self-Appraisal and Social Comparison02:57

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According to Charles Cooley, we base our image on what we think other people see (Cooley 1902). We imagine how we must appear to others, then react to this speculation. We don certain clothes, prepare our hair in a particular manner, wear makeup, use cologne, and the like—all with the notion that our presentation of ourselves is going to affect how others perceive us. We expect a certain reaction, and, if lucky, we get the one we desire and feel good about it. But more than that, Cooley...
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Accuracy, limits, and approximations are common in many fields, especially in engineering calculations. These concepts are imperative for ensuring that a given value is as close as possible to its true value.
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Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
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埋め込み可能なループレコーダーの精度:マルチセンター,マルチデバイスの比較

Suraya H Kamsani1, Melissa E Middeldorp2, Shaun Evans2

  • 1Centre for Heart Rhythm Disorders, Adelaide University and Royal Adelaide Hospital, Adelaide, South Australia, Australia; Cardiology Department, National Heart Institute, Kuala Lumpur, Malaysia.

JACC. Clinical electrophysiology
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PubMed
まとめ
この要約は機械生成です。

埋め込み式ループレコーダー (ILR) は,不規則なリズムを検出する際の精度が異なっており,多くの誤警報が臨床作業量を増加させる. この負担を軽減するために,ILRアラートアルゴリズムの改善が必要である.

キーワード:
アリズミーの検知偽陽性警報についてです.埋め込み式ループレコーダー (ILR)遠隔モニタリング 遠隔モニタリング

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科学分野:

  • 心臓病学 心臓病学
  • 医療機器 医療機器について
  • デジタル・ヘルス・デジタル・ヘルス

背景:

  • 挿入式ループレコーダー (ILR) は,長期の心臓モニタリングに不可欠です.
  • しかし,ILRによる頻繁な偽陽性警報は,医療従事者の臨床的負担を大幅に増加させる.

研究 の 目的:

  • 4つの主要なILRデバイスのリズム障害検出精度を評価および比較する.
  • この研究では特にメドトロニックLINQ II,ボストンサイエンティフィックLUX-Dx,バイオトロニックバイオモニターIII,アボットコンファームRx.を評価した.

主な方法:

  • 6,756人の患者から,ECGで確認された437,351回のエピソードを含む大規模なマルチセンターデータベースが利用されました.
  • 詳細な分析のために1,140人の患者のランダムなサンプルが選択され,医師によって判断された警告がありました.

主要な成果:

  • ボストン・サイエンティフィック LUX-Dxは,心房低心筋梗塞/心筋梗塞および心筋梗塞の検出において,最も高い陽性予測値 (PPV) を示した.
  • Medtronic LINQ IIとAbbott Confirm RxはPPVが適度であったが,Biotronik Biomonitor IIIは心房不全症/AFでPPVが最も低いことを示した.
  • アボット・コンファーム・Rxのパウズ検出は,主にアンダーセンシングによるもので,アボット・コンファーム・Rxのパウズ検出は最悪で,ボストン・サイエンティフィック・LUX-Dxのパウズ検出は最高でした.

結論:

  • 現在の埋め込み式ループレコーダーは,心拍不全の検出において,変数精度を示しています.
  • アルゴリズムの改良にもかかわらず,多くの偽陽性警報がすべてのテストされたデバイスで持続しています.
  • ILRアラートアルゴリズムのさらなる進歩は,偽アラートに関連する臨床的負担を軽減するために不可欠です.