経口内視鏡筋切除術後のリフルス食道炎の発生率と予測要因: 2年間の見通し研究
Praveer Rai1, Prabhat Kumar Verma2, Ankit Mishra2
1Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, 226014, Uttar Pradesh, India. praveer_rai@yahoo.com.
Digestive diseases and sciences
|February 13, 2026
まとめ
アハラシア・カルディアの口腔内視鏡性筋切除 (POEM) は,胃食道逆流症 (GERD) に繋がる可能性があります. 対象性GERDは,POEMの2年後に症状性GERDよりも頻繁に発生し,ほとんどの症例は軽度で酸性ではない.
科学分野:
- 胃腸内科 胃腸内科
- 内視鏡外科手術について
- 胃食道逆流性疾患の研究
背景:
- 口腔内視鏡筋切除術 (POEM) は,アハラシア・カルディアの治療に有効です.
- POEMには反流症防止メカニズムがなく,GERDのリスクを高めています.
- GERDの発生率とPOEM後の予測要因を評価することは極めて重要です.
研究 の 目的:
- POEM後のGERDの2年間の発生率を決定するために.
- POEM後のGERD発達の予測要因を特定する.
- 客観的および症状的なGERDの割合を比較するために.
主な方法:
- POEM後のアハラシア患者50人を対象とした前向きな研究.
- 検証されたアンケートによるGERDの評価 (症状).
- 目的は,pHインペダンスと食道胃二管管内視鏡を用いたGERDの評価である.
主要な成果:
- 目標 GERDは42% (pH阻害) と14% (内視鏡検査) で検出されました.
- 症状のあるGERDは,患者の18%で報告されています.
- ほとんどのGERD症例は軽度で,侵食性および酸性がない.
結論:
- 客観的なGERDは,POEMの2年後の症状的なGERDよりもより一般的です.
- POEM後のGERDの発生率は,腹腔鏡ヘルラー筋切除 (LHM) と比較できます.
- 症状性GERDの有意な予測要因は特定されなかった.
キーワード:
24時間のpH測定法GERD ゲルドとはヘラーズ・マイ・オット・ミー経口内視鏡性ミオトミー (peroral endoscopic myotomy) とは,経口内視鏡性ミオトミー (peroral endoscopic myotomy) とは,経口内視鏡性ミオトミー (peroral endoscopic myotomy) とは,経口内視鏡性ミオトミー (peroral endoscopic myotomy) とは,経口内視鏡性ミオトミー (peroral endoscopic myotomy) とは,経口内視鏡性ミオトミー (peroral endoscopic myotomy) とは,経口内視鏡性ミオトミー (peroral endoscopic myotomy) とは,関連する概念動画
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