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Updated: Feb 14, 2026

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GAL3ST1媒介ヒストンチロシン硫化ががん関連フィブロブラストによって誘発され,胃がんの転移を促進する

Yifan Lu1, Xiongyan Wu1, Baolong Li1

  • 1Shanghai Key Laboratory of Gastric Neoplasms, Shanghai Institute of Digestive Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine Shanghai China.

Cancer research
|February 13, 2026
PubMed
まとめ

この研究は,がんに関連した線維芽細胞が胃がん (GC) の転移をどのように促進するかを明らかにしています. 重要な酵素であるGAL3ST1はヒストンを改変し,腫瘍の拡散と上皮細胞-メゼンキーマ移行 (EMT) を推進する遺伝子を活性化させます.

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