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Updated: Feb 15, 2026

Identification of EGFR and RAS Inhibitors using Caenorhabditis elegans
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サブクリニカル・プライマリ・アルドステロニズムとeGFRの低下

Gregory L Hundemer1,2, Louis-Charles Desbiens3, Mohsen Agharazii4,5

  • 1Department of Medicine, Division of Nephrology, University of Ottawa, Ottawa, Ontario, Canada.

Journal of the American Society of Nephrology : JASN
|February 13, 2026
PubMed
まとめ

アルドステロンとレニンの比率 (ARR) の上昇によって示されるサブクリニック原発アルドステロン症は,腎臓機能の低下がより迅速に起こることに関連しています. 低レニンのレベルは,血圧に関係なく,推定グルメルフィルタレーション率 (eGFR) の低下の増加と相関しています.

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