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Updated: Feb 15, 2026

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins
11:34

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins

Published on: August 9, 2019

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単細胞RNA配列解析によるメンデルのランダム化により,効果記憶CD4+T細胞が,ミアステニアグラビスのリスク因子として特定されました

Zhaolin Ren1, Hao He2, Zhichun Cai2

  • 1Department of Neurology, Yuexi Hospital of the Sixth Affiliated Hospital, Sun Yat-sen University (Xinyi People's Hospital), Xinyi, Guangdong, China.

Medicine
|February 13, 2026
PubMed
まとめ

遅発性ミアステニア・グラビス (LOMG) のリスクは,エフェクター記憶CD4+T細胞と関連しています. これらの細胞は,TGF-βおよびIL-4によって潜在的に影響を受け,この自己免疫神経筋結節疾患の新たな治療標的を示唆し,危機の際に膨張します.

キーワード:
メンデルのランダム化エフェクターメモリ CD4+ T細胞ミアステニア・グラヴィス単細胞RNAシーケンシング

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