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Updated: Feb 15, 2026

Stem-cell Based Engineered Immunity Against HIV Infection in the Humanized Mouse Model
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Stem-cell Based Engineered Immunity Against HIV Infection in the Humanized Mouse Model

Published on: July 2, 2016

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Rhesus V2アペックスノッキンマウスモデルでのHIV-1中和幅の迅速な獲得は,単一のボラス免疫接種後に行われた

Amrit Raj Ghosh1, Rumi Habib2,3, Nitesh Mishra4,5

  • 1Batista Lab, Ragon Institute of Mass General Brigham, MIT, and Harvard, Cambridge, MA 02139, USA.

Science immunology
|February 13, 2026
PubMed
まとめ

特殊なマウスモデルでの新しい生殖線を標的とするトリマーによる単一の免疫は,HIV-1に対する広範に中和する抗体 (bnAbs) を成功裏に生成しました. このアプローチは,将来のHIVワクチンの開発を簡素化する可能性がある.

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