関連する実験動画
Updated: Feb 15, 2026

10:33
Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis
Published on: December 17, 2021
3.2K
メソトレキサートとミコフェノラートモフェチルの組み合わせ 耐火性尿道炎と硬化症:症例シリーズ
Parthopratim Dutta Majumder1, Ahana Sen1, Rakshita Kene1
1Department of Uvea & Intraocular inflammation, Sankara Nethralaya, College Road, Chennai, Tamil Nadu.
Retinal cases & brief reports
|February 13, 2026
まとめ
メトトレキサートとミコフェノラートモフェチルの併用療法により,耐火性ウベイトスおよび硬化症が効果的に治療されました. この免疫抑制的アプローチにより,重度の眼炎の患者でコルチコステロイドを大幅に減らすことができました.
科学分野:
- オフタルモロジック (眼科)
- 免疫学 免疫学とは
- レウマトロジーの病理学
背景:
- 膀炎と硬化症は,視力の低下につながる炎症性目の疾患です.
- 治療に耐性のある症例では,しばしば高度な免疫抑制療法が必要になります.
- 従来の治療法では,有効性が限られ,副作用が大きくなる可能性があります.
研究 の 目的:
- メトトレキサートとミコフェノラートモフェチルの組み合わせの有効性と安全性を評価する.
- 治療に抵抗性のあるウエビチスおよび硬化症の患者におけるこの併用治療の評価.
主な方法:
- 耐火性ウヴェイチスまたは硬化症の患者の遡及的チャートレビュー.
- 疾患の寛解とコルチコステロイド離脱を含む治療結果の分析.
- 併用療法に関連する有害事象の評価.
主要な成果:
- 軟膜炎の患者全員が寛解を達成し,硬化症の患者も治療に反応した.
- コルチコステロイドの治療を大幅に減らすか,完全に中止することは可能でした.
- 併用療法は一般的によく許容され,1人の患者が副作用を経験しました.
結論:
- 併用された経口メトトレキサートとミコフェノラートモフェチルは,重症,耐火性ウベイトスおよび硬化症の有効な治療法です.
- この治療戦略は,コルチコステロイドへの依存を減らすことができます.
- 長期的な結果と最適な投与レジメンを探求するためのさらなる研究は可能である.
関連する概念動画
Resistors In Series
6.8K
A resistor is an ohmic device that limits the flow of charge in a circuit. Most circuits have more than one resistor. If several resistors are connected together and connected to a battery, the current supplied by the battery depends on the equivalent resistance of the circuit. The equivalent resistance of a combination of resistors depends on both their individual values and how they are connected. The simplest combination of resistors is the series combination.
In a series circuit, the...
In a series circuit, the...
6.8K
Series Resonance
887
The RLC circuit impedance is defined as the ratio of the supply voltage to the circuit current. Resonance in such a circuit occurs when the imaginary part of this impedance equals zero. This specific condition means that the inductive reactance is exactly equal to the capacitive reactance. The frequency at which this happens is known as the resonant frequency. Mathematically, the resonant frequency is inversely proportional to the square root of the product of the inductance (L) and capacitance...
887
Series and Parallel Capacitors
9.8K
Capacitors, fundamental components in electronic circuits, can be connected in series and/or parallel configurations. Each configuration has different impacts on the overall behavior of the circuit.
First, consider capacitors connected in series to a battery. In this configuration, the plate connected to the battery's positive terminal develops a positive charge, while the plate attached to the negative terminal becomes negatively charged. An equal magnitude of charge is induced on the...
First, consider capacitors connected in series to a battery. In this configuration, the plate connected to the battery's positive terminal develops a positive charge, while the plate attached to the negative terminal becomes negatively charged. An equal magnitude of charge is induced on the...
9.8K
Trigonometric Fourier series
838
Fourier series is a foundational mathematical technique that decomposes periodic functions into an infinite series of sinusoidal harmonics. This method enables the representation of complex periodic signals as sums of simple sine and cosine functions, facilitating their analysis and interpretation in various fields, including signal processing, acoustics, and electrical engineering.
The trigonometric Fourier series specifically expresses a periodic function with a defined period T using sine...
The trigonometric Fourier series specifically expresses a periodic function with a defined period T using sine...
838
Convergence of Fourier Series
439
The Fourier series is a powerful mathematical tool for representing periodic signals as an infinite sum of complex exponentials. In practice, this infinite series is truncated to a finite number of terms, yielding a partial sum. This truncation makes the approximation of the signal feasible but introduces certain challenges, particularly near discontinuities, known as the Gibbs phenomenon.
The Gibbs phenomenon refers to the persistent oscillations and overshoots that occur near discontinuities...
The Gibbs phenomenon refers to the persistent oscillations and overshoots that occur near discontinuities...
439
Series R—L Circuit Transients
434
In a series resistor-inductor (R-L) circuit, closing the switch at the start of the time period simulates a three-phase short circuit, a fault condition where all three phases of an unloaded synchronous machine are short-circuited. When there is no fault impedance and no initial current, the initial voltage is determined by the phase angle of the source voltage.
Using Kirchhoff's Voltage Law (KVL) to analyze this circuit helps determine the total asymmetrical fault current, which consists...
Using Kirchhoff's Voltage Law (KVL) to analyze this circuit helps determine the total asymmetrical fault current, which consists...
434

