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Updated: Feb 15, 2026

A Method to Assess Bacteriocin Effects on the Gut Microbiota of Mice
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腸内微生物群が加齢マウスの薬物動態の変動に影響する:効果は薬剤によって異なります

Qing-Xuan Xie1, Xiao-Na Zeng1, Yun-Hui Wang1

  • 1Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, Hunan, China; Hunan Key Laboratory of Pharmacogenetics, Institute of Clinical Pharmacology, Central South University, Changsha, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China; FuRong Laboratory, Changsha, Hunan, China; National Engineering Research Center of Personalized Diagnostic and Therapeutic Technology, Changsha, Hunan, China.

Drug metabolism and disposition: the biological fate of chemicals
|February 13, 2026
PubMed
まとめ

腸内微生物群は,老齢マウスの薬物代謝に大きく影響し,フェナセチンとミダゾラムの暴露に影響します. 腸内微生物の除去は,デクストロメソルファン曝露の年齢関連の変化を逆転させ,個別化された高齢者医薬品を支援しました.

キーワード:
老化とは,老化です.腸内微生物群 (gut microbiota) は,腸内微生物群 (gut microbiota) と呼ばれている.パーソナライズされた医療ファルマコキネティックの変化

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