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Updated: Feb 15, 2026

Chinese Herbal Retention Enema for the Treatment of Ulcerative Colitis
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HSP90をコヴェラント的に天然の小分子コスチュノリドで標的にして,死滅と潰瘍性大腸炎を阻害します

Shan Yang1, Yunsen Zhang2, Yuying Shi3

  • 1College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China; TCM Prevention and Treatment of Metabolic and Chronic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China; Institute of High Altitude Multimorbidity/TCM-Integrated High-Altitude Medicine Center, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.

International immunopharmacology
|February 13, 2026
PubMed
まとめ

コストヌーロライド (CTL) は,潰瘍性大腸炎 (UC) モデルにおける熱ショックタンパク質90 (HSP90) を標的にすることで死滅を抑制する. この新しい治療法は,炎症と腸の損傷を効果的に軽減し,UC治療の有望な戦略を提供します.

キーワード:
大腸炎 (大腸炎) が発症しました.コストノライド コストノライドコヴァラント結合は,コヴァラント結合で結ばれます.HSP90は,HSP90と一致しています.ネクロプトーシス (Necroptosis) とは

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