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Updated: Feb 15, 2026

A Combined 3D Tissue Engineered In Vitro/In Silico Lung Tumor Model for Predicting Drug Effectiveness in Specific Mutational Backgrounds
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線形と3Dの分子特性を組み合わせた統一されたフレームワークで,強力な薬物-タンパク質相互作用の予測を実現します

Chang Sun1, Zichen Qin2, Minglei Li1

  • 1Centre for Bioinformatics and Intelligent Medicine, College of Computer Science, Nankai University, Tianjin 300071, China.

Cell reports methods
|February 13, 2026
PubMed
まとめ

PointDPIは,線形と3Dの特性を用いて薬物-タンパク質相互作用 (DPI) を予測し,目に見えない分子の精度を向上させます. 4つの予測されたDPIは実験的に検証され,様々な疾患に対する治療的可能性を示しました.

キーワード:
3D分子構造 3D分子構造CP: 計算生物学についてPDE4Bは,PDE4Bと一致している.マルチモダルの構造の整合トポロジカルな関係を保存する トポロジカルな関係を保存する湿った実験室での実験

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