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Updated: Feb 15, 2026

Chemical Reversion of Conventional Human Pluripotent Stem Cells to a Naïve-like State with Improved Multilineage Differentiation Potency
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Chemical Reversion of Conventional Human Pluripotent Stem Cells to a Naïve-like State with Improved Multilineage Differentiation Potency

Published on: June 10, 2018

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素朴な多能性からの脱出は,変数の遅延とともに進行するが,人口の異質性を生み出すための非対称的な分割なしに進行する

Stanley E Strawbridge1, Clelia Corridori2, Guy B Blanchard3

  • 1Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Department of Biochemistry, University of Cambridge, Cambridge CB2 1QR, UK.

Stem cell reports
|February 13, 2026
PubMed
まとめ

マウスの胚性幹細胞は不可逆的に分化し,形成性多能性への移行は相関する姉妹細胞行動を示します. 微分化のタイミングは細胞周期に依存していないので,非同期的な出口が多能性を保護することを示唆しています.

キーワード:
セルトラッキング セルトラッキングコミットメント コミットメント コミットメント コミットメント差異化差異化とは胚性幹細胞とは形成的な多能性である.数学的モデリング数学モデリングによる数学的モデリング幹細胞幹細胞とはシンメトリック・ディビジョン

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