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Updated: Feb 15, 2026

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses
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Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses

Published on: May 6, 2019

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CD8+ T細胞の腫瘍細胞に対する細胞毒性を研究するためのフローサイトメトリーベースの測定法

Alexey V Sarapulov1, Marc-Anthony Rodriguez1, Roberta Zappasodi2

  • 1Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, United States.

Methods in cell biology
|February 13, 2026
PubMed
まとめ

この研究では,がん細胞のCD8+T細胞殺戮を測定するためのフローサイトメトリプロトコルが導入されています. この方法は,T細胞媒介の細胞毒性を定量化することによって,がん免疫療法の有効性を正確に評価します.

キーワード:
細胞毒性T細胞について細胞毒性アッセイ 細胞毒性アッセイ 細胞毒性アッセイ 細胞毒性アッセイフローサイトメトリーアッセイ

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