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Updated: Feb 15, 2026

Spatiotemporal Control of Protein Activity through Optogenetic Allosteric Regulation
08:00

Spatiotemporal Control of Protein Activity through Optogenetic Allosteric Regulation

Published on: October 4, 2024

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アロステル調節とヒトのフォスフォリボシルホルミールグリシナミジンシンタゼの触媒結合の構造的および分子的基礎

Nandini Sharma1, Weijie Zhou2,3, Jarrod B French4

  • 1The Hormel Institute, University of Minnesota, Austin, MN, 55912, USA.

Nature communications
|February 13, 2026
PubMed
まとめ

研究者らは,ピュリン生物合成における重要な酵素であるフォスフォリボシルフォームグリシンアミジン合成酵素の構造を明らかにした. これは,がんの代謝と潜在的な新薬標的の洞察を提供します.

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