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Updated: Feb 15, 2026

Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration
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Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration

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病気の結腸組織におけるeQTLは,IBDに関連した潜在的な標的遺伝子を特定します

Nina C Nishiyama1,2, Sophie Silverstein2,3, Kimberly Darlington2,4

  • 1Curriculum in Bioinformatics and Computational Biology, Department of Genetics, School of Medicine, Department of Biology, College of Arts and Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Nature communications
|February 13, 2026
PubMed
まとめ

炎症性腸疾患 (IBD) の結腸組織における発現定量特征局部 (eQTL) 分析を使用して,研究者は108のIBD局部のための194の潜在的な標的遺伝子を特定しました. 病気の組織eQTLの研究は,IBD変異の影響を理解するために不可欠です.

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