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Updated: Feb 15, 2026

Interphase Fluorescence in situ Hybridization of Bone Marrow Smears of Multiple Myeloma
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Interphase Fluorescence in situ Hybridization of Bone Marrow Smears of Multiple Myeloma

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Y染色体に関連したEIF1AYの削除は,多発性骨髄腫における性差を誘発する

Zuxi Feng1,2, Jun Bai2, Yanhong Li2

  • 1Department of Hematology, Lanzhou University Second Hospital, Lanzhou, China.

NPJ precision oncology
|February 13, 2026
PubMed
まとめ

Y関連遺伝子のEIF1AYは,男性多発性骨髄腫 (MM) の腫瘍抑制剤として作用する. EIF1AYの喪失は,マクロファージの活動に影響を及ぼし,癌の成長を促し,男性特異免疫療法のターゲットとしてEIF1AYを示唆しています.

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