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Updated: Feb 15, 2026

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併発性口腔炎の痛みおよび/または消音不全を有する患者およびそれのない患者におけるキセロストミア
Yoon-Jai Hwang1, Hong-Seop Kho1,2
1Department of Oral Medicine and Oral Diagnosis, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, South Korea.
Journal of oral rehabilitation
|February 14, 2026
まとめ
乾燥口腔 (キセロストミア) の重症度は,単独で発生した場合,唾液腺の機能と関連しています. しかし,口腔乾燥が口腔の灼熱の痛みや聴覚障害に伴う場合,心理的苦痛と症状の強度がより重要な要因になります.
科学分野:
- 口腔医学は,口腔医学というものです.
- 歯科の研究 歯科の研究
- 症状学研究 症状学研究
背景:
- 乾口症の重さは,多くの場合,客観的な唾液流量と相関関係がない.
- 併発する口腔の灼熱性痛みや消音不全が,キセロストミアに与える影響は,まだ十分に理解されていない.
研究 の 目的:
- 口腔の灼熱の痛みおよび/または聴覚障害が,キセロストミアの認知された重症性にどのように影響するかを調査する.
- 症状の呈現に基づいて,キセロストミアの重症性に寄与する要因を区分する.
主な方法:
- 口の乾燥を呈した396人の患者の遡及的分析.
- クセロストミア単独 (146人の患者) と口腔の灼熱の痛み/消音障害 (250人の患者) を伴うクセロストミアとの分類.
- アンケート,唾液流量検査,カンジダ菌培養,心理的評価によるデータ収集;分析に多重線形回帰を用いた.
主要な成果:
- グループ間のセルフ報告されたキセロストミアの重度の有意な差は認められなかった.
- クセロストミア単独では,重症度が唾液流量が低く,カンジダ菌のコロニー化がより高いと相関していました.
- 疼痛/消音不全を伴うキセロストミアでは,痛みの重さは味覚障害,口腔の痛みの強度,心理的苦痛と強く相関し,唾液流量との相関は弱かった.
結論:
- 孤立した症例におけるクセロストミアの重症度は,主に唾液腺の機能と関連している.
- 併発性口腔の灼熱性疼痛/失聴症のキセロストミアの場合,症状の重度と心理的苦痛は唾液流量よりも大きな影響を及ぼします.
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