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Updated: Feb 15, 2026

Imaging Mycobacterium tuberculosis in Mice with Reporter Enzyme Fluorescence
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ミトコンドリアの局所化されたFABP4は,ミトコンドリアのホメオスタシスを維持することによって,フェロプトーシスに依存したMycobacterium tuberculosisの拡散を阻害する

Tingting Zhao1, Xinyu Hu1, Ju Li1

  • 1State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, College of Basic Medical Sciences, Jilin University, Changchun, China.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
|February 14, 2026
PubMed
まとめ

マイコバクテリウム結核感染症は,ミトコンドリア脂肪酸結合タンパク質4 (FABP4) を抑制し,病原体の拡散を促進します. FABP4の回復はフェロプトーシスを阻害し,細菌の増殖を減少させ,結核の新たな治療目標を提供します.

キーワード:
ファブp4 ファブp4 ファブp4フェロプトーシス (ferroptosis) とは脂質過酸化による脂質過酸化ミトコンドリアのホメオスタシス結核 (結核病) とは

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