日中に屋外で過ごした時間と,英国バイオバンク参加者の生物学的年齢加速との関連
Jia-Dong Ning1, Pan-Pan Zhu1, Xiaofeng Ma1
1State Key Laboratory of Multi-Organ Injury Prevention and Treatment, Department of Biostatistics, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, Guangdong, China.
International journal of environmental health research
|February 14, 2026
まとめ
適切な時間を毎日,特に夏には2時間,冬には1時間,屋外で過ごすことは,生物学的老化を遅らせることに関連しています. この最適な時間を超えると,老化が加速する可能性がありますが,より短い時間は,老化マーカーにも悪影響を及ぼします.
科学分野:
- ゲロントロジーはゲロントロジーの学科です.
- 環境衛生 環境衛生 環境衛生
- バイオ統計学 バイオ統計学
背景:
- 生物学的年齢 (BA) 加速は,老化のマーカーであり,ライフスタイル要因の影響を受けます.
- 日中に屋外で過ごす時間 (TOD) は,健康と老化に影響を与える潜在的に変更可能な要因です.
研究 の 目的:
- 昼間に屋外で過ごす時間 (TOD) と生物学的年齢加速との関連を調査する.
- 生物学的年齢加速を緩和するためにTODの最適な期間を決定する.
主な方法:
- 生物学的年齢加速は,クレメラ・ドゥーバル法BA (KDM-BA) と表型年齢 (PhenoAge) の残留値を用いて,年代的年齢に対して計算された.
- 汎用添加モデルを使用して,夏と冬のBA加速とTODの関連性を評価しました.
主要な成果:
- KDM-BA加速を最小限に抑えるための最適なTODは,夏には1日2時間,冬には1時間でした.
- PhenoAgeの加速のための最適なTODは,KDM-BA.より約1時間長かった.
- 両方のBAメトリックは,TODが最適なレベルを超えたときに加速を示し,PhenoAgeの加速は,両方の季節にTODが最適以下で減少し,KDM-BAは冬にのみ負の関連を示した.
結論:
- 適切な日中の屋外活動時間は,健康的な老化を促進する上で重要な役割を果たします.
- TODの特定の期間は,季節によって異なる生物学的年齢加速の減少と関連しています.
- 最適なTODを理解することで,健康的な老化のための公衆衛生戦略を伝えることができます.
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