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Updated: Feb 15, 2026

An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment
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高リスク高齢患者における用量最適化のためのアピキサバン製薬動態の活用

Rachel Goldstein1,2, Khaled Sandouka1, Lana Zighan1

  • 1Department of Medicine, Faculty of Medicine, Hadassah Medical Center Mt. Scopus, The Hebrew University of Jerusalem, 91905, Jerusalem, Israel.

Clinical pharmacokinetics
|February 14, 2026
PubMed
まとめ

高齢患者のアピキサバン濃度のモニタリングと投与量の調整を繰り返し行うことで,治療薬のレベルが改善されました. この介入は,この高リスクグループにおいて,出血および血栓塞栓性イベントを予防するのに役立ちます.

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