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関連する概念動画

Sampling Methods: Sample Types01:18

Sampling Methods: Sample Types

3.3K
Sampling materials are classified into three main types: solid, liquid, and gas.
Solid samples include a variety of substances, such as sediments from water bodies, soil, metals, and biological tissues. Two standard methods for extracting sediments from water bodies are grab sampling and piston coring. Grab sampling involves using a device to collect a discrete sediment sample from the bottom of a water body with minimal disturbance. Grab samples do not always represent the entire area due to...
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Convenience Sampling Method00:55

Convenience Sampling Method

11.7K
Sampling is a technique to select a portion (or subset) of the larger population and study that portion (the sample) to gain information about the population. Data are the result of sampling from a population. The sampling method ensures that samples are drawn without bias and accurately represent the population.
Convenience sampling is a non-random method of sample selection; this method selects individuals that are easily accessible and may result in biased data. For example, a marketing...
11.7K
Sampling Methods: Overview01:06

Sampling Methods: Overview

3.5K
A sample refers to a smaller subset representative of a larger population. In analytical chemistry, studying or analyzing an entire population is often impractical or impossible. Therefore, samples are used to draw inferences and generalize the whole population. The sampling method selects individuals or items from a population to create a sample. Standard sampling methods include random, judgemental, systematic, stratified, and cluster sampling. 
In analytical chemistry, the choice of...
3.5K
Systematic Sampling Method01:17

Systematic Sampling Method

13.4K
Sampling is a technique to select a portion (or subset) of the larger population and study that portion (the sample) to gain information about the population. Data are the result of sampling from a population. The sampling method ensures that samples are drawn without bias and accurately represent the population. Because measuring the entire population in a study is not practical, researchers use samples to represent the population of interest.
Systematic sampling is one of the simplest methods...
13.4K
Stratified Sampling Method01:16

Stratified Sampling Method

15.6K
Sampling is a technique to select a portion (or subset) of the larger population and study that portion (the sample) to gain information about the population. The sampling method ensures that samples are drawn without bias and accurately represent the population. Because measuring the entire population in a study is not practical, researchers use samples to represent the population of interest.
To choose a stratified sample, divide the population into groups called strata and then take a...
15.6K
Cluster Sampling Method01:20

Cluster Sampling Method

14.9K
Appropriate sampling methods ensure that samples are drawn without bias and accurately represent the population. Because measuring the entire population in a study is not practical, researchers use samples to represent the population of interest.
To choose a cluster sample, divide the population into clusters (groups) and then randomly select some of the clusters. All the members from these clusters are in the cluster sample. For example, if you randomly sample four departments from your...
14.9K

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Updated: Feb 16, 2026

Immunohistochemistry Test for the Lyssavirus Antigen Detection from Formalin-Fixed Tissues
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Immunohistochemistry Test for the Lyssavirus Antigen Detection from Formalin-Fixed Tissues

Published on: October 26, 2021

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フォーマルリン固定組織サンプルに対するマルチプレックス免疫ヒストケミストリーの現在の方法.

Romana Hendrychová, Kateřina Čížková, Dominik Hraboš

    Ceskoslovenska patologie
    |February 14, 2026
    PubMed
    まとめ
    この要約は機械生成です。

    マルチプレックス免疫ヒスト化学 (mIHC) は,腫瘍の微小環境の空間分析を進めており,従来の方法の限界を克服しています. 診断にさらに統合するには,がんの特徴と治療を改善するために標準化が必要です.

    キーワード:
    デジタル病理学 デジタル病理学免疫光は,免疫光である.質量スペクトロメトリによる質量スペクトロメトリです.マルチプレックス免疫ヒストロケミストリー

    さらに関連する動画

    Standardized Processing for Formalin-Fixed, Paraffin-Embedded Cell Pellet Immunohistochemistry Controls
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    Proteomic Sample Preparation from Formalin Fixed and Paraffin Embedded Tissue
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    Proteomic Sample Preparation from Formalin Fixed and Paraffin Embedded Tissue

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    関連する実験動画

    Last Updated: Feb 16, 2026

    Immunohistochemistry Test for the Lyssavirus Antigen Detection from Formalin-Fixed Tissues
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    Standardized Processing for Formalin-Fixed, Paraffin-Embedded Cell Pellet Immunohistochemistry Controls
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    Proteomic Sample Preparation from Formalin Fixed and Paraffin Embedded Tissue
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    Proteomic Sample Preparation from Formalin Fixed and Paraffin Embedded Tissue

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    科学分野:

    • 病理学 パトロジー
    • 免疫ヒストキミストリー
    • がん研究 がん研究

    背景:

    • H&E染色や染色体IHCのような伝統的なヒト病理学的方法は,複数のバイオマーカーを検出し,空間的な細胞関係を分析する上で限界があります.
    • マルチプレックス免疫ヒスト化学 (mIHC) は,複数のエピトープの同時検出とFFPE組織における詳細な空間分析を可能にすることで,これらの制限を克服します.
    • 腫瘍の微小環境の特徴づけは,がん治療を変革した免疫療法の開発に不可欠です.

    研究 の 目的:

    • フォーマルリン固定パラフィン埋め込み組織 (FFPE) の分析のためのマルチプレックス免疫ヒスト化学 (mIHC) 方法の能力を検討する.
    • クロモゲン,免疫光,核酸結合抗体,質量スペクトロメトリーを含むmIHC検出技術の進歩について議論する.
    • mIHCを日常的な臨床診断に統合する際の課題と将来の展望を強調する.

    主な方法:

    • 現代の複合免疫ヒスト化学 (mIHC) 技術のレビュー.
    • 様々な検出戦略の議論: 連続サイクルラベリング,チラミン信号増幅,核酸結合抗体,質量スペクトロメトリー.
    • 標準化,抗体検証,データ分析,規制面を含む課題の分析.

    主要な成果:

    • mIHCは,複数のバイオマーカーを同時に検出し,腫瘍のマイクロ環境内の細胞集団の空間分析を可能にします.
    • ヌクレオチド結合抗体や質量スペクトロメトリーなどの高度な技術は,特異性,定量分析,広範なバイオマーカープロファイリングの強化を提供します.
    • 技術の進歩にもかかわらず,日常的な臨床統合は,標準化,検証,データ分析,規制の障害に直面しています.

    結論:

    • マルチプレックス免疫ヒスト化学 (mIHC) は,詳細な腫瘍微環境分析のための伝統的な方法よりも重要な利点を提供しています.
    • 病理学の継続的な自動化とデジタル化は,臨床実務におけるmIHCのより広範な採用を推進すると予想されています.
    • mIHCの成功統合は,より深い腫瘍の特徴づけと,患者の治療結果の改善を約束します.