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Updated: Feb 16, 2026

Time-Lapse 2D Imaging of Phagocytic Activity in M1 Macrophage-4T1 Mouse Mammary Carcinoma Cells in Co-cultures
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Time-Lapse 2D Imaging of Phagocytic Activity in M1 Macrophage-4T1 Mouse Mammary Carcinoma Cells in Co-cultures

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AANG: 非小細胞肺がんにおけるマクロファージ-ミオフィブロブラストの移行を標的とする天然化合物製剤

Max Kam-Kwan Chan1, Philip Chiu-Tsun Tang1, Zoey Zeyuan Ji1

  • 1Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China.

Phytomedicine : international journal of phytotherapy and phytopharmacology
|February 14, 2026
PubMed
まとめ

研究者らは,マクロファージ-ミオフィブロブラストトランジション (MMT) を,非小細胞肺がん (NSCLC) の前発がん関連フィブロブラスト (CAF) の源として特定した. 最適化された伝統的な中国医学 (TCM) の配方であるAANGは,臨床前モデルにおいてMMTとがんの進行を効果的に阻害しました.

キーワード:
がんに関連した線維芽細胞.マクロファージ-ミオフィブロブラストの移行自然化合物療法とは,自然化合物療法です.非小細胞性肺がんは,小細胞性肺がんではない.Smad3/Smad7のシグナルを送っている.腫瘍のマイクロ環境

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