関連する実験動画

Updated: Feb 16, 2026

Complementation of Splicing Activity by a Galectin-3 - U1 snRNP Complex on Beads
08:48

Complementation of Splicing Activity by a Galectin-3 - U1 snRNP Complex on Beads

Published on: December 9, 2020

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ガレクチン-3BPの構造的複雑性を,統合的計算型抗体設計ワークフローを通じて克服する

Andrielly H S Costa1, Eduardo M Gaieta1, Aline O Albuquerque2

  • 1Postgraduate Program in Computational and Systems Biology, Oswaldo Cruz Foundation (Fiocruz), 21040-900, Rio de Janeiro, Brazil; Structural and Functional Biology in Biopharmaceuticals Group - Fiocruz Ceará, 61760-000, Eusébio, Brazil.

Computers in biology and medicine
|February 14, 2026
PubMed
まとめ

研究者らは,ガレクチン-3結合タンパク質 (Gal-3BP) を標的とした抗体を設計するための計算方法を開発し,グリコシル化などの課題を克服しました. 癌に対する治療開発のために最適化された抗体候補が特定されました.

キーワード:
抗体工学とは,抗体工学である.エピトープスクリーニングガレクチン-3結合タンパク質ガウス加速分子ダイナミクスグリコタンパク質は,

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