関連する実験動画

Updated: Feb 16, 2026

Directed Dopaminergic Neuron Differentiation from Human Pluripotent Stem Cells
06:40

Directed Dopaminergic Neuron Differentiation from Human Pluripotent Stem Cells

Published on: September 15, 2014

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ヒトの多能幹幹細胞の分化過程におけるトランスゲンサイレンシングの予防

Takeshi Uenaka1, Alan Napole2, Aninda Dibya Saha2

  • 1Institute for Stem Cell Biology & Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA; The Phil & Penny Knight Initiative for Brain Resilience at the Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA.

Cell stem cell
|February 14, 2026
PubMed
まとめ

新しいTK4 PiggyBacベクターは,幹細胞の分化中にトランスゲンサイレンシングを防止します. このシステムは,従来の方法の限界を克服し,さまざまな研究アプリケーションのための安定した遺伝子発現を保証します.

キーワード:
PiggyBacベクトルについてUCOEは,UCOEと一致している.WPREはWPREと一致している.クロマチンの断熱器人間の多能性幹細胞マイクログリアのミクログリアニューロン ニューロンプロモーター・アクティビティのプロモーター活動セーフハーバー・ロカス (Safe Harbour Locus) とは,安全な港の位置である.トランスゲンサイレンシングどこにでもあるクロマチンの開口要素である.ウッドチャックの肝炎は,転写後の規制要素である.

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