lncRNA媒介ネットワークをターゲットに,がんにおけるドクソルビシン抵抗性を克服する

Mengru Qiu1, Zhaoting Wang2, Yuanyin Teng3

  • 1Department of Occupational Pulmonary Disease, Shandong Academy of Occupational Health and Occupational Medicine, Occupational Disease Hospital of Shandong First Medical University (Shandong Province Hospital Occupational Disease Hospital), Jinan, Shandong, China.

PubMed
まとめ

長いノンコーディングRNAs (lncRNAs) は,主要ながん経路を調節することによって,ドクソルビシン (DOX) 化学療法に対する耐性を駆動します. これらのlncRNAをターゲットにすることは,薬剤耐性を克服し,がん治療を改善するための有望な戦略です.

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