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Updated: Feb 16, 2026

Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization
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Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization

Published on: July 27, 2021

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多様な集団からのxQTLと全ゲノム関連研究を組み合わせることで,薬効性遺伝子の発見が改善されます

Noah Lorincz-Comi1,2, Wenqiang Song1,2, Xin Chen1,2

  • 1Cleveland Clinic Genome Center, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH, USA.

Nature communications
|February 14, 2026
PubMed
まとめ

この研究は,アルツハイマー病や統合失調症のような複雑な疾患に対する新しい薬物の標的を特定するために,遺伝子ベースの関連テストのための新しい枠組みであるGenTを導入しています. 実験的検証により,アルツハイマー病の治療の可能性が確認されました.

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