子どもの近視制御のための4つの介入の臨床的効果と費用対効果:単一センターの遡及研究
Daohuan Kang1, Lu Yuan1, Carla Lanca2,3
1Department of Ophthalmology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Children and Adolescents' Health and Diseases, Hangzhou, 310052, Zhejiang Province, China.
Scientific reports
|February 14, 2026
まとめ
リピートされた低レベル赤光 (RLRL) 治療は近視のコントロールにおいて最も高い有効性を示し,一部の患者は軸の縮小を経験しました. 近視制御メガネレンズ (MCSL) は,子供の近視の管理に最適な費用対効果を提供します.
科学分野:
- オフタルモロジック (眼科)
- 小児眼鏡検査について
- 臨床光学についてです.
背景:
- 近視は,子どもたちの公衆衛生上の懸念が高まっています.
- 効果的な近視制御戦略は,高い近視と関連する眼の合併症を予防するために不可欠です.
- 現実の世界での様々な介入を比較することは,臨床的意思決定に不可欠です.
研究 の 目的:
- 4つの近視制御介入の1年間の臨床効果と費用対効果を比較するために:単一視野レンズ (SVL),近視制御メガネレンズ (MCSL),オーソケラトロジー (Ortho-K),および繰り返し低レベルの赤光 (RLRL) 治療.
- 遡及的観察コホート研究を使用して,現実世界の環境での介入を評価する.
- SVLと比較した各アクティブ介入のインクリメンタルコスト・効果比 (ICER) を決定する.
主な方法:
- 8歳から14歳の近視児206人を対象とした遡及的観察コホート研究.
- 介入には,SVL (n=50),MCSL (n=60),Ortho-K (n=44),RLRL (n=52) が含まれていた.
- 1年後の軸長 (AL) と球体等価折射 (SER) の変化. 2次結果:ICER. 2次結果:ICER. 2次結果:ICER. 3次結果:ICER. 4次結果:ICER. 4次結果:ICER. 5次結果:ICER. 4次結果:ICER. 5次結果:ICER. 4次結果:ICER. 5次結果:ICER. 5次結果:ICER. 6次結果:ICER. 5次結果:ICER. 6次結果:ICER. 7次結果:ICER.
主要な成果:
- すべての積極的介入は,SVLと比較してAL延長を大幅に減少させました (平均AL変化:0.42 mm/年).
- RLRLは最も高い有効性を示した (平均AL変化:0.06mm;SVLと比較して86.0%),31%が軸縮小を経験した.
- MCSL (0.23 mm AL変化; 45.2%の有効性) は,最も費用対効果の高い介入 (保存された0.1 mm ALあたり151.69ドル),次にRLRL (184.13ドル) であった. Ortho-K (0.18 mm AL変化; 57.5%の有効性) は最高ICER (400.42ドル) を有しました.
結論:
- RLRL治療は,近視制御における1年で最も高い有効性を示し,患者のサブセットで軸縮小が観察され,RCTでのさらなる調査を正当化しました.
- MCSLメガネレンズは,有効性と経済的実現性をバランスとしながら,最も費用対効果の高い近視制御オプションです.
- オートホー-Kは非常に効果的ですが,MCSLとRLRLと比較してより高い財務コストに関連しています.
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